Founded in 1977, Spoleto is one of America’s premier performing arts festivals. For 17 days and nights that begins the Friday of Memorial Day weekend, Spoleto fills Charleston with renowned artists and on-the-rise performers in disciplines including opera, theater, dance, and a wide range of music—from symphonic and chamber to choral, jazz, and folk. Slated performers for this year’s festival include Yo-Yo Ma, Old Crow Medicine Show, Trombone Shorty & Orleans Avenue, and many more. Typically, Spoleto puts on 150 performances in more than 10 different venues and even produces its own operas.  Multiple venues in Charleston, including The College of Charleston, Charleston Gaillard Center, Dock Street Theatre, Festival Hall, and more. Dates, showtimes vary, as do ticket prices, so check the website. (843) 579-3100, www.spoletousa.org